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Novo Nordisk: After the clinical trial results of kidney therapy were released, European regulators gave Ozempic a positive label evaluation.Russia said it would not make concessions on the Ukrainian issue and hoped to make contact with the US. Russian Foreign Ministry spokesman Zacharova said at a regular press conference on the 11th local time that Russia would not make concessions on the Ukrainian issue in response to the negotiation proposal put forward by US President-elect Trump on the 8th, and hoped to make contact with the US, but so far it has not received any "serious suggestions" from the team of US President-elect Trump. Zacharova also said that the recent statement of Ukrainian President Zelensky showed that "achieving peace is not a priority for Ukraine". Zelensky reiterated a few days ago that Uzbekistan will not sign any kind of peace agreement without security guarantee.The Dow opened up 0.04%, the S&P 500 fell 0.2%, the Nasdaq fell 0.4% and Adobe fell 10.4%, and the fiscal year performance guidance fell short of expectations. General Dynamics fell 2.8% and was bearish by institutions. Uber rose by 3.5%, and its volume dropped by nearly 6% yesterday. CFO said that the mobile business will grow steadily. Jinshan Cloud rose 2.5%, and UBS sharply raised its target price to $12.5.

Adobe(ADBE.O) fell by 12%, the biggest one-day drop since March 15th.American stock index futures maintained a downward trend, with S&P 500 E-MINI futures down 0.3%, Nasdaq futures down 0.6% and Dow Jones futures down 0.1%.Market News: Doctors say Brazilian President Lula is fully capable of signing official documents.

European Central Bank President Lagarde: We must be very cautious. European Central Bank President Lagarde: We must be very cautious because service prices and wages are rising rapidly. Financial difficulties are self-created uncertainties.Sixty-two kinds of drugs entered the centralized procurement. The tenth batch of centralized procurement was organized by the state, and the tenth batch of centralized procurement was opened in Shanghai on December 12, resulting in the result of quasi-selection. 62 kinds of drugs were successfully purchased, and 385 products from 234 enterprises were qualified for quasi-selection, involving hypertension, diabetes, tumors, cardiovascular and cerebrovascular diseases and other fields. The results of the proposed selection will be officially released after publicity. Since 2018, the National Medical Insurance Bureau has organized 10 batches of state-organized drug collection with relevant departments, and successfully purchased 435 kinds of drugs. (Xinhua News Agency)Institutional analysis of the European Central Bank's interest rate resolution: the European Central Bank cut interest rates by 0.25 percentage points, aiming to stabilize the economy that was hit by French debt concerns and trade tariffs that were highly exposed to the threat of US President-elect Trump.